The primary distinction between IUI and IVF lies in the location where fertilization occurs. In the case of IUI, fertilization takes place internally, as the sperm is directly injected into the womans uterus. Consequently, if successful, the resulting embryo implants within the uterus.

In the case of IVF, fertilization is external, occurring outside the uterus within a laboratory setting.  Oocytes are extracted from the ovaries after a stimulation process and fertilized with sperm in a laboratory. If fertilization is successful, the embryo is inserted into the uterine cavity. Pregnancy can usually be confirmed in a week.

IVF was originally developed for women with blocked tubes or missing fallopian tubes. IVF is also used when other conditions such as endometriosis or male infertility is present.

Our experts will review your history and guide you to the most appropriate treatment and diagnostic procedures.

• No sperm or a very low number of sperm, inability of the sperm to move progressively (low motility) and poor morphology (size and shape of the sperm).
• Chronic ailments such as cancer
• Environmental factors: Exposure to radioactive chemicals
• Lifestyle factors: Being overweight, smoking, drinking alcohol

• Age
• Endometriosis
• Hormonal issues leading to ovulation problems
• Tubal blockage
• Fibroids
• Lifestyle factors: Being overweight, smoking, drinking alcohol, unhealthy diet

Women are born with approximately 2 million eggs in their ovaries. Before a girl reaches puberty, about 11,000 eggs die every month. Thus, in her teenage years, a woman has about 300,000 to 400,000 eggs available. From this point onwards, about 1000 eggs are utilised every month. This has nothing to do with any form of birth control, pregnancy, hormone production, health, lifestyle or nutritional supplements. Eventually, a woman reaches menopause when she has no viable eggs left.

PCOS (Polycystic Ovarian Syndrome) refers to a condition caused by hormonal imbalances. Women suffering from PCOS produce higher than normal amounts of male hormones. This affects ovulation and can result in irregular periods. In some cases, women suffering from PCOS may have irregular periods. This, in turn, can make it harder for these women to conceive. In fact, PCOS is one of the most common causes of female infertility.

Endometriosis is a common disorder found in women, where the endometrial tissues grow outside the uterus. This gynaecological condition can occur in the ovaries, fallopian tubes, the tissues lining the pelvis, and in rare cases, abdominal cavity, too.

• Pelvic pain
• Abnormal bleeding
• Painful urination
• Painful sex
• Nausea or vomiting
• Difficulty in getting pregnant
• Low immunity

Cryopreservation is the process of freezing eggs, sperm or embryos to sub-zero temperatures for later use. When the eggs, sperm or embryos are needed, they are thawed and fertilized or used in a fertility treatment cycle. Sperm may be used for intrauterine insemination (IUI) or in vitro fertilization (IVF) procedures.

• Oocyte cryopreservation, also known as egg freezing, is a process wherein a womans eggs are extracted, frozen and stored for later use.
• Cryopreservation can prove to be extremely beneficial for women who have been diagnosed with cancer and are scheduled for some kind of oncological treatment like radiotherapy or chemotherapy
• Women who are unmarried or are in a situation that is not conducive to childbearing, can also opt for oocyte cryopreservation. (Fertility Preservation)

It is important to recognize that the rate of birth defects in humans in the general population is about 3% of all births for major malformations and 6% if minor defects are included. Fortunately, 20-plus years following Louise Browns birth (the first IVF baby), we now have ample data that children conceived through IVF have no increase in these rates of birth defects due to the technique itself.

A minor rise in abnormalities is ascribed to the infertility and age factor of the intending parents. Further follow-up on older children indicates that IVF children have done as well or better than their peers in academic achievement (probably a social bias) and have no higher rates of behavioural or psychological difficulties.

• Avoid fast foods. Eat more home cooked meals instead.
• Use vegetable oil for cooking.
• Include more vegetable proteins such as fresh beans and nuts.
• Avoid pasta, rice and sweets.
• Choose full-fat milk and yogurt over skimmed ones.
• A multivitamin with folic acid and vitamin B helps.
• Avoid red meat. Increase intake of fruits and beans for iron.
• Avoid beverages and drink more water.
• Aim for an ideal body weight.
• Some form of exercise is always good.

PGT-A is genetic testing performed on embryos to identify numerical chromosomal abnormalities or aneuploidy. This test is performed on embryos prior to transfer into the uterus. By analysing all embryos generated in an IVF treatment cycle, those free of chromosomal aneuploidy can be identified for selective transfer. As a result, the pregnancy rates per transfer are increased and the miscarriage rates decreased.

PGT-M involves testing of embryos for specific monogenic disorders like thalassemia, haemophilia and certain types of muscular dystrophy. It helps couples who have a family history or those who have had a child affected with these disorders to have an unaffected child.

All embryos formed as a part of an Assisted Reproductive Technology (ART) are tested for this specific monogenic disorder. Only unaffected or carrier embryos are transferred to have a disease-free child. This can also be combined with PGT-A to further improve success rates.

• When you’ve been trying to conceive for an extended period of time: If you and your partner have been trying to conceive for a year (if youre under 35) or six months (if you're over 35) without success, it's a good time to consider consulting a fertility specialist. IVF might be recommended as a potential option if other less invasive treatments have not worked.


• Known Fertility Issues: If you or your partner have known fertility issues such as blocked fallopian tubes, severe male factor infertility, endometriosis, or polycystic ovary syndrome (PCOS), it might be advisable to consult a fertility specialist earlier in your journey.


• Age: As a womans age advances, the quality and quantity of her eggs decrease, making it more difficult to conceive. If you're over 35 and have been trying to conceive for six months without success, it's a good idea to consult a fertility specialist sooner rather than later.


• Recurrent Pregnancy Loss: If youve experienced multiple miscarriages, its important to seek specialized care to determine the underlying causes and explore potential solutions, which might include IVF with preimplantation genetic testing (PGT) to select embryos with a higher chance of success.

• For your 1st free consultant with a doctor, call 0777 783 377 or 0778 779 110.
• To meet a Fertility Specialist, call 225, 990 or visit a channeling counter at Asiri any Asiri Hospital, Asiri Laboratory or Collection Center or use the Web Link: Doc990