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Bone Marrow Transplant Unit

Bone Marrow Transplant Unit

If you have been diagnosed with a condition that requires a bone marrow transplant you will be directed to the medical experts at the Bone Marrow Transplant (BMT) Unit.  

What is Bone Marrow?

Your bone marrow performs the important task of producing all the blood cells your body needs.  They are derived from haematopoietic stem cells (HSCs) which are located in the bone marrow.

Therefore, many diseases of blood and bone marrow such as thalassaemia, leukaemia etc. can be cured by removing the diseased bone marrow and replacing it with bone marrow or HSCs from a healthy donor. 

A bone marrow transplant is a procedure that allows doctors to replace damaged or destroyed bone marrow – the soft tissue inside your bones – with healthy bone marrow stem cells.

Bone marrow can be collected relatively easily and donated with no significant consequences to the donor thanks to its great capacity for self-regeneration. A Bone Marrow Transplant (BMT) is mainly a medical rather than a surgical procedure.

Types of diseases and transplantations:

  • Autologous - Inherited disorders that runs in families: Thalassemia, immune deficiencies. An autologous transplant is one which uses a person's own stem cells. These cells are collected in advance and reintroduced to the person at a later stage. This type of transplant is useful in patients with multiple myeloma.
  • Allogenic - Acquired diseases that are not hereditary: Myeloma, Aplastic Anemia, High Grade Lymphoma, and Leukemia. In an allogeneic transplant, the patient receives bone marrow from another person -- usually a HLA compatible sibling, but sometimes an unrelated donor. This type of transplant is used to correct severe disorders such as thalassaemia and aplastic anaemia. It involves a long stay in the hospital (approximately 45 days)

For both types of diseases, blood transfusion (cleaning the patients blood) will be required as the bone marrow recovers.

Contact Point:

Direct Hotline: +94 76 625 8941
Email: chlbmt@asiri.lk 

 

What sets us apart

Take a look at what differentiates the Asiri Central Bone Marrow Transplant Unit from the rest. 

  • 3 state-of-the-art rooms with positive-pressure ventilation and Hepa Filtration
  • Nationally Recognized Medical Panel
  • Lab Tests (HLA typing tests) that are sent directly to New York to ensure an accurate match with donor and recipient

What to expect

  • On Admission date, patient arrives at Central Hospital and admitted to the Bone Marrow Unit directly.
  • A central line is inserted.
  • Once the central line is inserted successfully, conditioning regime begins for the patient (IE: Drug Protocol). The patient is kept in a positive air facilitated room. 
  • These days are known as Minus Days (Before Transplant).
  • 4-5 days before transplant date, donor is given GCSF to stimulate the bone marrow HSC (OPD). 
  • 1 day before the surgery, the donor is admitted to the unit directly.
  • Donor is sent to the Theater and the bone marrow is harvested under general anesthesia or Peripheral Blood Stem Cells are harvested by Apheresis. 
  • Amount of stem cells collected is estimated and if an adequate amount is collected , the product is directly transfused to the patient via the Central Line.
  • This is considered Day 0.
  • Referred to as Plus Days. 
  • Patient is under closely monitored. This includes blood investigation and vital care. 
  • Neutrophil count drops to 0.
  • Due to this condition, the patient is highly prone to infections and complication. They need transfusions of blood and platelets.
  • Anti-viral and fungal prophylaxis to prevent infections according to the protocol.
  • Avoid raw and under-cooked meat, as well as deli, processed, and cured meats (including salami, bologna, hot dogs, and ham) unless heated until steaming hot. 
  • Avoid smoked seafood, typically labeled as “lox,” “kippered,” “nova style,” or “jerky.” 
  • Avoid raw fish and shellfish. 
  • Avoid raw and under-cooked eggs. 
  • Avoid salad bars, buffets, and potlucks. 
  • Avoid unpasteurized products, such as unpasteurized dairy items (like milk, cheese, and eggnog), as well as unpasteurized honey, juice, and cider. 
  • Avoid fresh and packaged foods that are past their “use by” and expiration dates. 
  • Avoid consuming raw sprouts of any kind, including alfalfa, clover, radish, and mung bean sprouts. 
  • Avoid leftovers older than 48 hours. It is important to follow proper food storage and reheating guidelines if you plan to prepare food ahead of time or save leftovers.
  • Children will have a High Protein diet

 

Results

We have completed over 50 Bone Marrow Transplants and have had patients complete successive yearly treatments. 

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011 466 5500